Craig D. Hardman – Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset

Автор: Craig D. Hardman
Название книги: Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset
Формат: PDF
Тема: Медицина
Количество страниц: 518
Качество: Изначально компьютерное, E-book

Developing better therapies for neurological conditions such as Parkinson’s and Alzheimer’s diseases remains an enduring problem for 21st century medicine. The testing of novel therapies will continue to require a robust experimental animal model. The marmoset is an ideal animal model for modern neurological research because of the species’ convenient body size, ease of handling, and the fundamental similarity of its neuroanatomy to the human brain.

The Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus) is the most detailed atlas of the marmoset brain available. An essential tool for researchers developing more effective therapies for disabling and debilitating neurological disorders, the book contains:

Fully delineated, high-quality (400x magnification) images of Nissl-stained, acetylcholinesterase histochemically-stained and parvalbumin, calbindin and neurofilament immunohistochemically-stained coronal and sagittal sections, as well as structural magnetic resonance images (MRI) for direct comparisons

Line diagrams with delineations of all cortical and subcortical structures, with grid overlays so the precise position of each structure can be located stereotaxically relative to the interaural line and infraorbital margin

Quantitative data regarding volume and cell number of many of the structures delineated in the atlas, regularly updated on an accompanying website

Standard nomenclature widely used in the Paxinos group of atlases, allowing users to compare and contrast homologous nuclei in different species using the major available atlases