P. Gopalakrishnakone – Spider Venoms (2016)

Автор: P. Gopalakrishnakone
Название книги: Spider Venoms
Формат: PDF
Жанр: Яды пауков
Страницы: 466
Качество: Изначально компьютерное, E-book

Spider venoms are a great and extensive source of bioactive compounds, and as such form a boundless and bountiful area awaiting us to discover and explore it. Springer’s Toxinology handbook series offers assistance in entering this vast and still largely uncharted territory, guiding through this tremendous space in – and hopefully for the enthusiastic reader-scientist also over – unprecedented ways.
Through biochemical characterization, structure-function studies, proteomics, bioinformatics, molecular biology, transcriptomics, and genomics of various spider species, our knowledge concerning venom components, toxins, and their mode of action has increased considerably over the years. It is by virtue of dedicated scientists that new toxins are discovered and that new insights arise, leading the way towards the investigation of their pharmacological effects and, hopefully, as a consequence, arriving at the discovery of venom components as new drug candidates.
Contents
Venoms
The Nonpeptide Low Molecular Mass Toxins from
Spider Venoms
The Venom of Australian Spiders
Venom of Cupiennius salei (Ctenidae)
Phoneutria nigriventer Venom and Toxins: A Review
The Venom from Lasiodora sp.: A Mygalomorph Brazilian Spider
Pain-Modulating Peptides in Spider Venoms: Good and Evil
Studying the Excitatory and Inhibitory Neurotransmissions with Spider Venoms
Phoneutria nigriventer Venom: Action in the Central Nervous System
Genes, Transcriptomes, and Bioinformatics
In Silico Modeling of Spider Toxins: Bioinformatics, Molecular Docking, and Molecular Dynamics
Spider Transcriptomes from Venom Glands: Molecular Diversity of Ion Channel Toxins and Antimicrobial Peptide Transcripts
Peptidome and Transcriptome Analysis of the Toxin-Like Peptides in the Venom Glands of Tarantula Grammostola rosea
Medical and Insecticidal
Spider Venom and Drug Discovery: A Review
Anticancer Potential of Spider Venom .
Hippasa Spider: Biology, Envenomation, Toxin Profiles, and Biological Functions – A Review
Recent Insights in Latrodectus (“Black Widow” Spider) Envenomation: Toxins and Their Mechanisms of Action
Antimicrobial, Insecticides, Analgesics, and Hyaluronidases from the Venom Glands of Brachypelma Spiders
Antimicrobial Peptides in Spider Venoms
Structural Diversity and Basic/Acidic Residue Balance of Active Cysteine-Rich Insecticidal Peptides from Spiders
Identifying Insect Protein Receptors Using an Insecticidal Spider Toxin
Loxosceles and Loxoscelism: Biology, Venom, Envenomation, and Treatment