J. Fishbein – Advances in Molecular Toxicology (8 Volume set)

Автор: J. Fishbein
Название книги: Advances in Molecular Toxicology (8 Volume set)
Формат: PDF
Жанр: Молекулярная токсикология
Страницы: 1900
Качество: Изначально компьютерное, E-book

1. Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.

Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed.

* Cutting edge reviews by leading workers in the discipline.
* In depth dissection of molecular aspects of interest to a broad range of scientists, physisicans and any student in the allied disciplines.
* Leading edge applications of technological innovations in the chemistry, biochemistry and molecular medicine.

2. Content:
Genotoxicity of Chromate
Drug-Induced Hepatotoxicity: Learning from Recent Cases of Drug Attrition
Glucuronidation-Dependent Toxicity and Bioactivation
Allergic Contact Dermatitis — A Common Skin Disease Caused by Allergic Reactions to Chemicals in Our Environment
Inorganic Molecular Toxicology and Chelation Therapy of Heavy Metals and
Pyrimidine Damage and Repair
Formation, Persistence and Significance of DNA Adduct Formation in Relation to Some Pollutants from a Broad Perspective

3. Content:
Recent Developments in Mediterranean Harmful Algal Events
Mechanism of Fiber Carcinogenesis: From Extranuclear Target to Transforming Growth Factor Signaling Pathway
Applications of Quadrupole-Linear Ion Trap Mass Spectrometry to the Analysis of Reactive Metabolites in Drug Discovery and Development
Molecular Aspects of Neurotoxins in Dopaminergic Neurons Molecular Mechanisms of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Lung Carcinogenesis
Disruption of Heme Synthesis by Polyhalogenated Aromatics
Aristolochic Acid Nephropathy: An Environmental and Iatrogenic Disease

4. Content:
Acrolein and the Lung: Chemical, Molecular, and Pathological Aspects
Potential Human Carcinogens
Recent Advances in Molecular Toxicology of Cadmium and Nickel
Fate of DNA Sugar Radicals
Nitric Oxide and Redox Inflammation in Cancer
Redox Chemistry of Biological Thiols
Toxicity of Silica Nanomaterials: Zeolites, Mesoporous Silica, and Amorphous Silica Nanoparticles
INDEX

5. Content:
Metal-Independent Pathways of Chlorinated Phenol/Quinone Toxicity
The Use of Proteomics in the Study of Molecular Responses and Toxicity Pathways in Biological Systems
The Molecular Toxicology of Chemical Warfare Nerve Agents
Toxicity of Metal Oxides Nanoparticles
Toxicity of Silver Nanomaterials in Higher Eukaryotes
Carboxymethylation of DNA Induced by N-Nitroso Compounds and Its Biological Implications

6. Content:
Bioactivation of Estrogens to Toxic Quinones
Diverse Mechanisms of Endogenous Nucleobase Deamination in DNA and RNA
Site-Specific Modification of the Electrophile Sensor Protein Keap1 and Activation of Nrf2-Dependent Gene Expression Genotoxicity of Chlorophenols and Ochratoxin A
Idiosyncratic Drug Reactions: Clinical Evidence for Mechanistic Hypotheses

7. Content:
AHR- and ER-Mediated Toxicology and Chemoprevention
Free Radical Metabolites in Arylamine Toxicity
Genotoxicity of Polycyclic Aromatic Hydrocarbon Metabolites: Radical Cations and Ketones
Nitrogen Oxides Toxicology of the Aerodigestive Tract
Noncholinesterase Protein Targets of Organophosphorus Pesticides
Organophosphate Exposure: Detection and Remediation

8. Volume 8 of Advances in Molecular Toxicology continues in the tradition of
sampling broadly from all corners of this diverse discipline. The editors
are confident that readers will enjoy this sampling that elaborates numerous
facets at the forefront of the field