M. Muller – Clinical Pharmacology. Current Topics and Case Studies (2nd edition, 2016)

Автор: M. Muller
Название книги: Clinical Pharmacology. Current Topics and Case Studies (2nd edition)
Формат: PDF
Жанр: Клиническая фармакология
Страницы: 398
Качество: Изначально компьютерное, E-book

Summarizes the latest topics, tools and clinical trials in clinical pharmacology
Added value for employees in drug research and development
This revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies. This updated book makes a valuable contribution to the field of Clinical Pharmacology and serves as a must-have guide for professors, researchers and advanced students from academia and pharmaceutical industry
Topics
Pharmacology / Toxicology
Pharmacy
Pharmacotherapy
Introduction
The Discipline of Clinical Pharmacology
Current Issues in Drug Development
Current Issues in Drug Regulation
Current Topics in Drug Reimbursement
Clinical Trials
Ethics in Clinical Research
Good Clinical Practice (GCP) and Scientific Misconduct
Phase I Studies and First-In-Human Trials
Clinical Trials: Interventional Studies
Observational Studies
Tools in Clinical Pharmacology
Tools in Clinical Pharmacology: Imaging Techniques
Pharmacokinetics II: 14C-Labelled Microdosing in Assessing Drug Pharmacokinetics at Phase 0
Current Concepts of Pharmacogenetics, Pharmacogenomics, and the “Druggable” Genome
Pharmacokinetics I: PK-PD Approach, the Case of Antibiotic Drug Development
Epidemiology and Biostatistics
Placebo Effects and Placebo Control in Clinical Trials
Topics in Clinical Pharmacology 16 Pharmaceutical Drug Safety
Drug Interactions
Development of Advanced Therapy Medicinal Products: A Case for Early Scientific Advice
Biologics
Generics, Biosimilars, Enantiomers, and Me-Toos
Orphan Drugs for Rare Diseases
Special Situations, Market Fragmentation II: Sex Differences
Special Situations III: Medicines for Children