S. Hansen – Bioanalysis of Pharmaceuticals
2.935 ₽
Автор: S. Hansen
Название книги: Bioanalysis of Pharmaceuticals
Формат: PDF
Тема: Медицина
Страницы: 333
Качество: Изначально компьютерное, E-book
Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids with an educational presentation of the principles, concepts and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the different types of biological samples and fluids that are used; how to prepare the samples by extraction, and how to perform the appropriate analytical measurements by chromatographic and mass spectrometric methods.
Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry:
Is an introductory student textbook discussing the different principles and concepts clearly and comprehensively, with many relevant and educational examples
Focuses on substances that are administered as human drugs, including low-molecular drug substances, peptides, and proteins
Presents both the basic principles that are regularly taught in universities, along with the practical use of bioanalysis as carried out by researchers in the pharmaceutical industry and in hospital laboratories
Is aimed at undergraduate students, scientists, technicians and researchers in industry working in the areas of pharmaceutical analyses, biopharmaceutical analyses, biological and life sciences
Описание
S. Hansen – Bioanalysis of Pharmaceuticals — это специализированное руководство по биологическому анализу лекарственных средств. Книга подробно рассматривает современные методы определения концентрации препаратов и их метаболитов в биологических матрицах: плазме, моче, тканях и других образцах.
Автор объясняет принципы разработки и валидации биоаналитических методик, включая жидкостную хроматографию, масс-спектрометрию (LC-MS/MS), иммуноанализ и другие техники. Особое внимание уделено регуляторным требованиям FDA, EMA и ICH, вопросам селективности, точности, стабильности образцов и минимизации матричных эффектов.
- специалистам по фармацевтическому анализу и биоаналитике
- разработчикам лекарств и сотрудникам контрактных лабораторий
- студентам и аспирантам фармацевтических и химико-биологических специальностей
- регуляторным специалистам и сотрудникам отделов контроля качества
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