M. Jansen — Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract (2016)

Автор: M. Jansen
Название книги: Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract
Формат: PDF
Жанр: Медицина
Страницы: 487
Качество: Изначально компьютерное, E-book

This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett's esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett's esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer.
Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer's Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.
Distal Esophageal Adenocarcinoma and Gastric Adenocarcinoma: Time for a Shared Research Agenda
Introduction
Clonal Evolution of Stem Cells in the Gastrointestinal Tract
The Complex, Clonal and Controversial Nature of Barrett’s Esophagus
A New Pathologic Assessment of Gastroesophageal Reflux Disease: The Squamo-Oxyntic Gap
Cancer Progression in the Distal Esophagus
Diagnosis by Endoscopy and Advanced Imaging of Barrett’s neoplasia
Endoscopic Treatment of Early Barrett’s Neoplasia: Expanding Indications, New Challenges
Definition, Derivation, and Diagnosis of Barrett’s Esophagus: Pathological Perspectives
What Makes an Expert Barrett’s Histopathologist?
Staging Early Esophageal Cancer
Transcommitment: Paving the Way to Barrett’s Metaplasia
Studying Cancer Evolution in Barrett’s Esophagus and Esophageal Adenocarcinoma
Genomics of Esophageal Cancer and Biomarkers for Early Detection
Common Variants Confer Susceptibility to Barrett’s Esophagus: Insights from the First Genome-Wide Association Studies
Cancer Progression in the Stomach
Endoluminal Diagnosis of Early Gastric Cancer and Its Precursors: Bridging the Gap Between Endoscopy and Pathology
Endoscopic Submucosal Dissection for Early Gastric Cancer: Getting It Right!
The Japanese Viewpoint on the Histopathology of Early Gastric Cancer
Syndromic Gastric Polyps: At the Crossroads of Genetic and Environmental Cancer Predisposition
Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future
Helicobacter pylori , Cancer, and the Gastric Microbiota
Helicobacter pylori and Gastric Cancer: Timing and Impact of Preventive Measures
Genomics Study of Gastric Cancer and Its Molecular Subtypes
Recapitulating Human Gastric Cancer Pathogenesis: Experimental Models of Gastric Cancer
Erratum To: Histopathological, Molecular, and Genetic
Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future