J. Dorszewska – Challenges in Parkinson’s Disease (2016)

Автор: J. Dorszewska
Название книги: Challenges in Parkinson's Disease (2016)
Формат: PDF
Жанр: Медицина
Страницы: 400
Качество: Изначально компьютерное, E-book

This book is a sum up of knowledge on the genetic factors and neuronal death mechanisms induced by excitotoxic and inflammatory agents. The authors summarize the pathophysiology observed both in patients with Parkinson's disease and in experimental models.
The book contains the latest views on drug therapy used in the treatment of parkinsonism and other therapeutic approaches for Parkinson's disease.
Parkinson's disease is a common neurological disease and affects 2% population of more than 65 years of age and 5% more than 85 years of age. Pathomechanism of this disease is still not fully understood.
Preface
Introductory Chapter – Genetic and Biochemical Factors in Parkinson’s Disease
Genetics of Parkinson’s Disease: The Role of Copy Number Variations
Mechanisms for Neuronal Cell Death in Parkinson’s Disease: Pathological Cross Talks Between Epigenetics and Various Signalling Pathways
Inflammation: Role in Parkinson's Disease and Target for Therapy
Chronic Inflammation Connects the Development of Parkinson’s Disease and Cancer
Is Chronic Systemic Inflammation a Determinant Factor in Developing Parkinson’s Disease?
Disorders of Sleep and Motor Control During the Impaired Cholinergic Innervation in Rat – Relevance to Parkinson’s Disease
Cognitive Impairment in Parkinson’s Disease: Historical Review, Past, and Present
Brain Network Metabolic Changes in Patients with Parkinsonian Tremors
Animal Models of Parkinson’s Disease
Understanding Pathophysiology of Sporadic Parkinson's Disease in Drosophila Model: Potential Opportunities and Notable Limitations
Pharmacotherapeutic Challenges in Parkinson’s Disease Inpatients
Clinical and Experimental Cell Therapy in Parkinson’s Disease
Cell-Based Therapies for Parkinson’s Disease: Preclinical and Clinical Perspectives
Stem Cell Therapy for Parkinson's Disease
Surgical Therapy of Parkinson's Disease
Neuro-Ophthalmologic Evaluation as a Biomarker for Diagnosis and Progression in Parkinson Disease
Possible Treatments of Atypical Parkinsonism
The Role of Nurses in Parkinson's Disease