M. A. Hayat – Cancer Imaging (2 Volume set)

Описание

The primary objective of this series, CANCER IMAGING,
is to present the readers with the most up-to-date
instrumentation, general applications, as well as specific
applications of imaging technology to diagnose
various cancers. The present work concentrates on the
application of this technology to the diagnosis of lung
and breast carcinomas, the two major worldwide
cancers.
In this work we discuss strategies for imaging cancer
and clinical applications of this technology and explain
the role of molecular imaging in early therapy monitoring.
In addition, we cover the following topics: synthesis
and use of different contrast agents, especially the
most commonly used tracer, 18F-fluorodeoxyglucose
(FDG), in conjunction with imaging modalities (e.g.,
magnetic resonance imaging [MRI]); the advantages
and limitations of the tracers; and rational and protocol
details of whole-body screening with computed tomography
(CT), positron emission tomography (PET), and
PET/CT. We also describe the role of imaging in drug
development, gene therapy, and therapy with monoclonal
antibodies; for example, we describe the advantages
of preclinical immuno-PET. The advantages of
hybrid modalities, such as PET/CT (e.g., in lung cancer),
are also presented.
The importance of the use of imaging for clinical diagnosis
is presented in detail, and the relationship between
radiation dose and image quality is discussed. In addition,
we present detailed methods for absorbed X-ray
dose measurement in mammography to avoid the risk of
radiation-induced carcinogenesis.
We also detail lung cancer screening, staging, and
diagnosing, applying different imaging modalities and
point out false-negative and false-positive images potentially
encountered in various body parts when imaged.
Imaging modalities, including high-resolution CT, thinsection
CT, computer-aided diagnosis with CT, low-dose
helical CT, and FDG-PET/CT, used for staging and diagnosing
lung cancer (e.g., non-small cell lung carcinoma),
are discussed.
Details of a large number of imaging modalities,
including optical mammography, digital mammography,
contrast-enhanced MRI, SPECT, color-Doppler
sonography, and sonography, used for diagnosing breast
cancer are presented. Other topics include use of imaging
for diagnosing invasive lobular carcinoma, density
of breast carcinoma, axillary lymph node status in
breast cancer, small-size primary breast cancer, and
microcalcification in breast lesions. The role of
Doppler sonography in differentiating benign and
malignant solid breast tumors is discussed, as are breast
scintigraphy and magnetic resonance spectroscopy of
breast cancer. Use of MRI for monitoring response to
breast cancer treatment is explained. Other methods
such as dynamic infrared imaging and thermography
are also presented.
This work consists of 61 chapters and has been developed
through the efforts of 132 authors and coauthors
representing 17 countries. The high quality of each manuscript
made my work as the editor an easy one. Strictly
uniform style of manuscript writing has been accomplished.
The results are presented in the form of both
black-and-white and color images that are appropriately
labeled.
I am indebted to the contributors for their promptness
in accepting my suggestions, and appreciate their
dedication and hard work in sharing their knowledge
with the readers. Each chapter provides unique individual,
practical knowledge based on the expertise of the
authors. The chapters contain the most up-to-date information,
and it is my hope that the book will be published
expeditiously.