M. Toi – Personalized Treatment of Breast Cancer (2016)

Автор: M. Toi
Название книги: Personalized Treatment of Breast Cancer
Формат: PDF
Жанр: Рак груди, рак молочной железы, болезни молочных желез, онкология, маммология, маммография
Страницы: 381
Качество: Изначально компьютерное, E-book

This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearance in patients with nodal metastasis, and the role of axillary surgery. Attention is also given to locoregional treatment after preoperative systemic therapy. Because therapeutic impact differs depending upon biological characteristics such as tumor subtype, local therapy should be based both on tumor biology and on therapeutic response in parallel. Associated translational research and mathematical prediction tools such as nomograms also are introduced. This book provides the essence of primary breast cancer care, particularly its individualization with novel therapeutic concepts and strategies, and will greatly benefit physicians and clinical investigators in breast cancer institutions.
Risk-Reducing Surgery for Breast Cancer Patients with BRCA Mutations.
Prophylactic Risk-Reducing Surgery for Breast Cancer.
Merits and Demerits of Practice for Hereditary Breast and Ovarian Cancer Syndrome (Advices and Issues).
Sentinel Lymph Node Biopsy and Neoadjuvant Chemotherapy in Breast Cancer Patients.
Axillary Reverse Mapping (ARM) as a Means to Reduce Lymphedema During Sentinel Lymph Node or Axillary Node Dissection.
Ultrasound for Axillary Staging.
One-Step Nucleic Acid Amplification (OSNA) Assay for Primary Breast Cancer.
Management of the Clinically Node-Negative Axilla in Primary Breast Cancer.
Lymphatic Mapping and Optimization of Sentinel Lymph Node Dissection.
Personalisation of Radiotherapy for Breast Cancer.
New Technologies in Radiation Therapy.
Radiotherapy Following Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer.
Novel Translational Research of Neo-adjuvant Endocrine Therapy.
Alterations of Biomarkers by Neoadjuvant Endocrine Therapy.
Essence of Neoadjuvant Therapy.
The Challenge to Overcome Triple-Negative Breast Cancer Heterogeneity.
Surgical Management of Breast Cancer After Preoperative Systemic Treatment.
Imaging of Tumor Response by Preoperative Systemic Treatment.
Human Epidermal Growth Factor Receptor (HER) Family Molecular Structure.
Locoregional Therapy Following Neoadjuvant Therapy for HER-2+ Breast Cancer: Opportunities and Challenges.
Nomograms to Predict Positive Resection Margin and to Predict Three or More Positive Lymph Nodes.
Practical Use of Nomograms.
Data Mining and Mathematical Model Development.