R. Shansky – Sex Differences in the Central Nervous System (2016)

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Автор: R. Shansky
Название книги: Sex Differences in the Central Nervous System
Формат: PDF
Жанр: Медицина
Страницы: 412
Качество: Изначально компьютерное, E-book

Sex Differences in the Central Nervous System offers a comprehensive examination of the current state of sex differences research, from both the basic science and clinical research perspectives. Given the current NIH directive that funded preclinical research must consider both females and males, this topic is of interest to an increasing percentage of the neuroscience research population.
The volume serves as an invaluable resource, offering coverage of a wide range of topics: sex differences in cognition, learning, and memory, sex hormone signaling mechanisms, neuroimmune interactions, epigenetics, social behavior, neurologic disease, psychological disorders, and stress. Discussions of research in both animal models and human patient populations are included.
Details how sex hormones have widespread effects on the nervous system and influence the way males and females functionAssists readers in determining how sex impacts their research and practice, and assists in determining how to adjust research programs to incorporate sex influencesIncludes discussions of research in both animal models and human patient populations, and at various developmental stagesFeatures revised and updated chapters by leaders in the field around the globe—the broadest, most expert coverage available
List of Contributors
Entitled to full text
Sex Differences in Immunity and Inflammation: Implications for Brain and Behavior
Molecular Mechanisms of Memory in Males and Females
Sex Differences in Anxiety Disorders: Gonadal Hormone Interactions with Pathophysiology, Neurobiology, and Treatment
Sex Differences in the Social Behavior Network and Mesolimbic Dopamine System
Sexual Dimorphisms in Psychosis Risk: A Neurodevelopmental Perspective
Sex Differences and Addiction
Stress and Emotional Learning in Humans: Evidence for Sex Differences
Biological Underpinnings of Sex Differences in Eating Disorders
The Maternal Brain: Short- and Long-Term Effects of Reproductive Experience on Hippocampus Structure and Function in Adulthood
Sex and the Developing Brain
Presence and Absence of Sex Differences in Structure and Function of the Brain Oxytocin System: Implications for Understanding the Regulation of Social Behavior
Sex Differences in Neurological Diseases
Steroid Hormone Signaling Pathways and Sex Differences in Neuroendocrine and Behavioral Responses to Stress
Sex Differences in Rodent Cognitive Processing and Responses to Chronic Stress
Epigenetic Sex: Gene–Environment Contributions to Brain Sex Differences and their Impact on Mental Health Risk
Subject Index

Описание

R. Shansky — Sex Differences in the Central Nervous System — фундаментальное научное издание, которое подробно разбирает, как половые различия влияют на строение, функционирование и патологии центральной нервной системы. Книга объединяет данные современной нейронауки, нейроэндокринологии и поведенческой биологии, показывая, почему стандартные «мужские» модели исследований часто не работают для женщин.

Автор анализирует механизмы полового диморфизма на молекулярном, клеточном и системном уровнях: от влияния половых гормонов на синаптическую пластичность до различий в стресс-реакциях, болевой чувствительности, когнитивных функциях и предрасположенности к неврологическим и психическим расстройствам. Особое внимание уделяется тому, как учитывать sex as a biological variable в экспериментах и клинических исследованиях.

  • нейробиологам и нейрофизиологам, изучающим мозг
  • специалистам в области психологии, психиатрии и гендерной медицины
  • студентам и аспирантам медицинских и биологических специальностей
  • исследователям, работающим с животными моделями и клиническими данными

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