F. Bertoldo — Bone Metastases from Prostate Cancer (2017)

Автор: F. Bertoldo
Название книги: Bone Metastases from Prostate Cancer
Формат: PDF
Жанр: Медицина
Страницы: 293
Качество: Изначально компьютерное, E-book

This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.
Table of contents
Biology and Pathophysiology of Bone Metastasis in Prostate Cancer
Markers of Bone Turnover in Bone Metastasis from Prostate Cancer
Bone Homing and Metastasis
Markers of Prostate Cancer: The Role of Circulating Tumor Markers in the Management of Bone Metastases
Circulating Tumor Cells (CTCs) and Metastatic Prostate Cancer (mPCa)
Nuclear Medicine Modalities to Image Bone Metastases with Bone-Targeting Agents: Conventional Scintigraphy and Positron-Emission Tomography
Detection of Bone Metastases and Evaluation of Therapy Response in Prostate Cancer Patients by Radiolabelled Choline PET/CT
Imaging of Glycolysis with 18F-FDG PET
New Radiopharmaceutical Markers for Metabolism and Receptor
Bone Metastases from Prostate Cancer: Hormonal Therapy
Chemotherapy
Combinations of Hormonal Therapy and Chemotherapy
Surgery: Treatment of Oligometastatic Disease
Bone Metastases from Prostate Cancer: Radiotherapy
Bone-Targeted Agents
Bone-Seeking Radionuclide for Therapy
New Frontiers in Treatment
Approaches for Assessment of Response of Bone Metastases to Therapies
Bone Metastases from Prostate Cancer: From Symptom Control to Pain Palliation
Economic Impact of Prostate Cancer Bone Metastases
Multidisciplinary Approach of Prostate Cancer Patients