Kevin W. Finkel – OncoNephrology (2020)
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Автор: Kevin W. Finkel
Название книги: OncoNephrology
Формат: PDF
Тема: Онконефрология
Количество страниц: 494
Качество: Изначально компьютерное, E-book
Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed.
Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy.
Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer.
Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment.
Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care.
Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects.
Описание
OncoNephrology — первое в своём роде руководство, посвящённое intersection онкологии и нефрологии. Кевин В. Финкель собрал актуальные данные о том, как рак и его лечение влияют на почки, а также как заболевания почек изменяют подход к терапии онкологических пациентов.
Книга подробно разбирает острую и хроническую почечную недостаточность на фоне химиотерапии, таргетной и иммунотерапии, синдром лизиса опухоли, электролитные нарушения, паранеопластические нефропатии, возможности проведения гемодиализа и трансплантации почки у онкологических больных. Особое внимание уделено лекарственной нефротоксичности современных противоопухолевых препаратов.
- Онкологам, желающим лучше понимать и предотвращать почечные осложнения
- Нефрологам, сталкивающимся с онкологическими пациентами
- Врачам отделений интенсивной терапии и трансплантологам
- Клиническим фармакологам и специалистам по лекарственной безопасности
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