V. Patel – Biomarkers in Bone Disease (2017)

Описание

In the present volume, Biomarkers in Bone Disease, we have sections on
1. General Aspects and Introductory Material
2. Body Fluids, Tissue, and Specific Biomarkers
3. Genetic, Histological, Physical, and Imaging Methods
4. Specific Diseases and Conditions
5. Resources
The editors recognize the difficulties in assigning particular chapters to particular
sections, as some chapters can fit into more than one section. Nevertheless, the book
has enormously wide coverage. Platforms and techniques include, for example,
“omics,” Raman spectroscopy, ultrasound, immunological, biochemical, histochemical
methods, and imaging. Conditions and biomedical areas encompass bariatric
surgery, bisphosphonate failure, bone quality, diabetes, effect of phytoestrogens,
effects of statins, ethnicity, exercise, fracture risk, gestational hypertension, glucocorticoid
treatments, HIV, intrauterine growth restriction, lumbar spine analysis,
osteoarthritis, osteogenesis imperfecta, osteopetrosis type II, osteoporosis, Paget’s
disease, physiology, prematurity, remodeling, Rett syndrome, sclerosing disorders,
sexual development, skeletal metastasis, spinal cord injury, and vascular remodeling.
Analytes and measures include acid phosphatase, adiponectin, alkaline phosphatase,
ameloblastin, calcium, carboxy-methyl lysine (CML), chitinases, creatine kinase,
gene expression, geometry, integrin alpha2beta1, natural radionuclides, osteocalcin,
parathyroid hormone, pentosidine, phosphorus, procollagen type 1 n-propeptide,
PTX3, quality of life, radiomorphometric indices, relaxin, sclerostin, sirtuins, trabecular
bone scores, ultrasound, uric acid, and vitamin D. There are also many other
analytes and conditions described within this volume.
Finally, the last chapter is devoted to locating resource material for biomarker
discovery and applications.
The chapters are written by national or international experts. This book is
designed for clinical biochemists, orthopedic specialists. rheumatologists, those
working within the wider field of skeletal disease, health scientists, epidemiologists doctors and nurses, from students to practioners at the higher level. It is also
designed to be suitable for lecturers and teachers in health care and libraries as a
reference guide.