Brad Bolon – Pathology of the Developing Mouse

Автор: Brad Bolon
Название книги: Pathology of the Developing Mouse
Формат: PDF
Тема: Ветеринария, Патология развития мышей
Страницы: 442
Качество: Изначально компьютерное, E-book

Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a “how to do” manual for developmental pathology experimentation in mice but, more importantly, a “how to interpret” resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity.

The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit:

baseline anatomic and physiologic traits of developing mice

principles of good experimental design and statistical analysis for mouse developmental pathology studies

procedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques;

methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids;