E. Song – The Long and Short Noncoding RNAs in Cancer Biology (2016)

Автор: E. Song
Название книги: The Long and Short Noncoding RNAs in Cancer Biology
Формат: PDF
Жанр: Медицина
Страницы: 455
Качество: Изначально компьютерное, E-book

Provides a comprehensive knowledge of long and short ncRNAs.
Chapters highlight recent advances in specific topics, like the molecular mechanisms of various classes of ncRNAs in cancer.
Contributed by experts in this field.
The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.
Noncoding RNAs: New Players in Cancers.
The Working Modules of Long Noncoding RNAs in Cancer Cells.
Methods to Study Long Noncoding RNA Biology in Cancer.
Relationship Between Noncoding RNA Dysregulation and Epigenetic Mechanisms in Cancer.
Noncoding RNAs in Growth and Death of Cancer Cells.
Noncoding RNAs in Cancer Cell Plasticity.
Noncoding RNAs in Regulation of Cancer Metabolic Reprogramming.
Noncoding RNAs in Tumor Angiogenesis.
Noncoding RNAs in Cancer Immunology.
Noncoding RNAs in Therapeutic Resistance of Cancer.
Noncoding RNAs Regulating Cancer Signaling Network.
Noncoding RNAs Regulating NF-κB Signaling.
Noncoding RNAs Regulating p53 and c-Myc Signaling.
Viral Noncoding RNAs in Cancer Biology.
Noncoding RNAs in Cancer Diagnosis.
Therapeutic Potentials of Noncoding RNAs: Targeted Delivery of ncRNAs in Cancer Cells.