P. Gopalakrishnakone – Venom Genomics and Proteomics (2016)
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Автор: P. Gopalakrishnakone
Название книги: Venom Genomics and Proteomics
Формат: PDF
Жанр: Биологические науки
Страницы: 464
Качество: Изначально компьютерное, E-book
This volume provides the reader with recent advances in the fields of molecular toxinology, the biotechnological applications of venom toxins, and antivenom production. The content of the twenty chapters of Venom Genomics and Proteomics illustrates not only the enormous progress made since the implementation of omics technologies in the field of toxinology, but one also realizes the road still ahead to reach a holistic view of venomous systems. Advancement in high-throughput technologies in the field of venomics has resulted in the ability to generate comprehensive venom profiles for many species. However, research on snake genomes is still in its infancy, although such studies are eagerly awaited to gain insights into the evolutionary history of snake venom proteins, including the mechanisms that originated venom and the regulation of toxin expression. Fortunately, this objective is also at the reach of current omic technologies. Therefore it would not be unrealistic to predict a bright near future to the field of molecular toxinology.
Venom Genomics and Proteomics covers research into the venom of scaled reptiles (lizards and snakes), scorpions, spiders, ants and platypuses. Special consideration is given to a number of observations made in the area of snake venom and in the application of advanced genomics and proteomics techniques on a variety of venom samples. The final chapters give some insight into the potential clinical uses of venom derivatives and into the importance and challenges faced in the production and quality control of antivenoms.
Topics
Pharmaceutical Sciences / Technology
Animal Biochemistry
Animal Physiology
Описание
Venom Genomics and Proteomics — это фундаментальное научное издание, посвященное молекулярному изучению ядов животных. Книга подробно рассматривает современные методы геномики, транскриптомики и протеомики, применяемые для анализа состава и эволюции ядовитых секретов змей, паукообразных, морских организмов и других представителей фауны.
Авторы анализируют, как генетические и белковые данные помогают понять механизмы действия токсинов, их структуру, вариабельность между видами и потенциал для разработки новых лекарственных препаратов и биотехнологических продуктов. Особое внимание уделено интеграции «омикс»-технологий и биоинформатики в venom research.
- Исследователям в области токсикологии, молекулярной биологии и эволюционной генетики
- Специалистам, работающим с ядами и природными токсинами
- Студентам и аспирантам биологических и медицинских направлений
- Биотехнологам, интересующимся созданием новых лекарств на основе природных молекул
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