C. Dahmann – Drosophila (2008)

Автор: C. Dahmann
Название книги: Drosophila
Формат: PDF
Жанр: Биологические науки
Страницы: 432
Качество: Изначально компьютерное, E-book

Drosophila is a comprehensive collection of methods and protocols for Drosophila, one of the oldest and most commonly used model organisms in modern biology. The protocols are written by the scientists who invented the methods. The text presents a diverse set of techniques that range from the basic handling of flies to more complex applications. This is the perfect reference manual for Drosophila researchers

Drosophila melanogaster has been the model system of choice for many investigators
over the past hundred years. Due to its long-standing tradition as a model
organism, many techniques used in Drosophila have been established and continue
to be developed to answer a variety of scientific questions. The recent invention
of techniques allowing the knock-down of genes by RNA interference and
gene replacement by homologous recombination are two important demonstrations
of the ongoing efforts to broaden the technical repertoire at hand for
researchers working with Drosophila. This volume is a collection of protocols
covering both standard techniques as well as novel methods. An introductory
chapter highlights the importance of Drosophila as a model system for the development
of Biology in the 20th century and review chapters provide concise and
up-to-date overviews on selected experimental systems.
This book makes no attempt to be comprehensive. A number of frequently used
standard techniques were selected and are described in-depth to allow novices to
get started with Drosophila. In addition, detailed protocols of recently developed
methods that we felt will become of broad use in the Drosophila community
within the next years are included.
I am grateful to Konrad Basler, Suzanne Eaton, Elisabeth Knust, Pavel
Tomancak, and Andreas Wodarz for alerting me to novel techniques and for their
advice on selecting the protocols for this book. I would also like to thank all the
authors for their expert contribution to this Volume.