A. Khan – Precision Molecular Pathology of Breast Cancer (2015)
3.475 ₽
Автор: A. Khan
Название книги: Precision Molecular Pathology of Breast Cancer
Формат: PDF
Жанр: Рак груди, рак молочной железы, болезни молочных желез, онкология, маммология, маммография
Страницы: 336
Качество: Изначально компьютерное, E-book
This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2.
Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.
Table of contents
Molecular Basis of Breast Cancer Imaging
Familial Breast Cancer and Genetic Predisposition in Breast Cancer
Modelling the Molecular Pathology of Breast Cancer Initiation
Molecular Pathology of Precancerous Lesions of the Breast
Breast Cancer Stem Cells: Role in Tumor Initiation, Progression, and Targeted Therapy
Molecular Pathology of Pre-Invasive Ductal Carcinoma
Molecular Pathology of Lobular Carcinoma
Molecular Pathology of Hormone Regulation in Breast Cancer: Hormone Receptor Evaluation and Therapeutic Implications
Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2 Evaluation and Role in Targeted Therapy
Molecular Classification of Breast Cancer
Triple-Negative Breast Cancer: Subtypes with Clinical Implications
Molecular-Based Diagnostic, Prognostic and Predictive Tests in Breast Cancer
Role of MicroRNAs in Breast Cancer
Molecular Pathology of Fibroepithelial Neoplasms of the Breast
Molecular Features of Mesenchymal Tumors of the Breast
Molecular Pathology of Breast Cancer Metastasis
The Molecular Pathology of Chemoresistance During the Therapeutic Response in Breast Cancer
The Molecular Pathology of Male Breast Cancer
Specimens for Molecular Testing in Breast Cancer
Описание
Precision Molecular Pathology of Breast Cancer — это современное руководство по молекулярной патологии рака молочной железы, вышедшее в 2015 году под редакцией А. Хана. Книга подробно рассматривает молекулярные механизмы развития опухолей груди, генетические мутации, сигнальные пути и возможности персонализированной диагностики.
Авторы анализируют ключевые биомаркеры, молекулярные подтипы рака молочной железы (Luminal A, Luminal B, HER2-enriched, Basal-like), методы молекулярного профилирования и их влияние на выбор терапии. Особое внимание уделяется роли NGS, FISH, IHC и другим технологиям в точной диагностике и прогнозировании ответа на лечение.
- патологам и молекулярным биологам, работающим в онкологии
- онкологам и маммологам, применяющим персонализированную медицину
- врачам-генетикам и специалистам по лабораторной диагностике
- аспирантам и исследователям в области онкопатологии
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