J. Raizer – Brain Metastases (2007)

Автор: J. Raizer
Название книги: Brain Metastases
Формат: PDF
Жанр: Медицина
Страницы: 236
Качество: Изначально компьютерное, E-book

Brain metastases are among the most feared and debilitating complication of
systemic cancer. They impact approximately 170 000 patients a year in the United
States, a number ten-fold greater than malignant gliomas. Historically, brain metastases
were diagnosed in patients with widespread systemic malignancy. Recent
improvements in systemic therapies are changing the incidence of brain metastases.
More patients are being diagnosed with brain metastases in the setting of controlled
systemic tumor.
In this book we provide succinct and up-to-date information to help manage
cancer patients who have the misfortune to develop brain metastases. A multidisciplinary
assessment involving neurosurgery, radiation oncology, neuro-oncology
and medical oncology is critical to optimize patient management and outcome.
While average survival remains poor, recent advances in surgery, radiation and
chemotherapy may improve disease control and quality of life for many patients.
We hope this book will not only serve as a reference for practitioners in oncology
but also stimulate ideas for future research.

1. Brain Metastases: Epidemiology and Pathophysiology . . . . . . . . . . . . . . . 1
Joohee Sul and Jerome B. Posner
2. The Economics of Brain Metastases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Charles L. Bennett MD PhD MPP, Cara C. Tigue BA,
and Karen A. Fitzner PhD
3. Neuroimaging of Parenchymal Brain Metastases . . . . . . . . . . . . . . . . . . . . 31
Matthew T. Walker, MD and Vipul Kapoor, MD
4. Symptom Management and Supportive Care
of the Patient with Brain Metastases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
Herbert B. Newton, M.D., FAAN
5. Surgery for Brain Metastases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Sunit Das M.D., Ph.D, Kenji Muro M.D. and Jeffrey J. Raizer M.D.
6. Radiation for Brain Metastases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
Malika L. Siker, M.D. and Minesh P. Mehta, M.D.
7. Dural and Skull Base Metastases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117
Arnaldo Neves Da Silva, M.D. and David Schiff, M.D.
8. Pediatric Brain Metastasis from Extraneural
Malignancies: A Review. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143
Stewart Goldman, MD, María E. Echevarría,
MD, Jason Fangusaro, MD
9. Brain Metastases in Hematologic Malignancies . . . . . . . . . . . . . . . . . . . . . 169
Nancy D. Doolittle, Ph.D.
10. Chemotherapy for Brain Metastases: Breast, Gynecologic
and Non-Melanoma Skin Malignancies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185
Gaurav D. Shah, MD and Lauren E. Abrey, MD
11. Chemotherapy for Brain Metastases
due to Lung Cancer and Melanoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199
Marc C Chamberlain, M.D.
12. Palliative Care for Patients With Brain Metastases. . . . . . . . . . . . . . . . . . 215