K. Sakuma – The Plasticity of Skeletal Muscle (2017)

Автор: K. Sakuma
Название книги: The Plasticity of Skeletal Muscle
Формат: PDF
Жанр: Медицина
Страницы: 295
Качество: Изначально компьютерное, E-book

This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis.

The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered.

Pluripotent Stem Cells and Skeletal Muscle Differentiation: Challenges and Immediate Applications
Role of the Ubiquitin-Proteasome Pathway in Skeletal Muscle
Stem Cell Therapy in Muscle Degeneration
The Autophagy-Dependent Signaling in Skeletal Muscle
Cytokines in Skeletal Muscle Growth and Decay
The Role of Ribosome Biogenesis in Skeletal Muscle Hypertrophy
Comprehensive Approach to Sarcopenia and Cachexia Treatment
The Role and Regulation of PGC-1’ and PGC-1“ in Skeletal Muscle Adaptation
Characteristics of Skeletal Muscle as a Secretory Organ
Biological Role of TRPC1 in Myogenesis, Regeneration, and Disease
ROS and nNOS in the Regulation of Disuse-Induced Skeletal Muscle Atrophy
Participation of AMPK in the Control of Skeletal Muscle Mass
Therapeutic Potential of Skeletal Muscle Plasticity and Slow Muscle Programming for Muscular Dystrophy and Related Muscle Conditions