Brian K. Nunnally – Prions and Mad Cow Disease

Автор: Brian K. Nunnally
Название книги: Prions and Mad Cow Disease
Формат: PDF
Тема: Бешенство у коров и крупно-рогатого скота, Прионы
Страницы: 444
Качество: Изначально компьютерное, E-book

The alarm sounded by Canada's recently confirmed case of bovine spongiform encephalopathy (BSE) has reaffirmed the exigency of establishing improved safeguards and more aggressive surveillance protocols in North America and around the world. Research converging on the probable causative agent-prion proteins-calls for intensive assessment of the headway gained in tracing prions, testing for transmissible neurodegenerative diseases, and developing methods for cornering the epidemic. Administered by an illustrious panel of 36 international contributors, this timely book marshals techniques for prion protein assay and diagnosis of transmissible spongiform encephalopathies (TSEs).

Contents
Foreword
Preface
Contributors
Taking Aim at the Transmissible Spongiform Encephalopathies Infectious Agents
Prions, the Protein Hypothesis, and Scientific Revolutions
A Simulation Model for Evaluating the Potential for Spread of Bovine Spongiform Encephalopathy in Animals or to People
Actions to Prevent Bovine Spongiform Encephalopathy from Entering the United States
Overview of Transmissible Spongiform Encephalopathy in Cervids in the United States
Bioassays for Prions
Cyclic Amplification of Scrapie Prion Protein: Implications for Diagnosis
The Enfer Transmissible Spongiform Encephalopathies Assay: Chemiluminescent ELISA of Prion Proteins
Sensitive Detection of Prion Proteins by Immunoassay: CEA/Bio-Rad Test
The Diagnosis of Transmissible Spongiform Encephalopathies Using Differential Extraction and DELFIA
In Vivo Diagnosis of Prion Diseases
Diagnosis of Prion Diseases by Multispectral Techniques
Detection of the Prion Protein in Blood Using a Fluorescence Immunoassay
Prion Detection and Application to the Safety of Biological Products
Index