Norman F. Cheville – Ultrastructural Pathology (Second edition)

Описание

Ultrastructural Pathology was originally designed for
pathologists who interpret cellular changes in lesions
encountered in the postmortem room. This edition has
shifted to an atlas format, reducing text and grouping
and labeling electron micrographs for easier identifi –
cation of organelles. Comparative pathology is again
emphasized, and has been strengthened by using diseases
that extend through different vertebrate species.
Ontogeny and phylogeny are basic concerns in comparative
medicine, particularly the tendency of closely
related animal species to suffer similar metabolic, neoplastic,
and infectious diseases. A section on diagnostic
electron microscopy has been added for those who
work day to day on disciplines that demand specialized
technologies for electron microscopy. Invertebrate
pathology is also included; although spontaneous
diseases of invertebrate species are not mirrors of their
counterparts in vertebrate animals, the biologic processes
are similar and at the level of the cell may even
be identical. One of the most exciting eras of pathology
was begun by observations on the infl ammatory
response of the water fl ea. Lastly, basic elements of
description—size, structure, and location in the cell—
are emphasized throughout the book.
Ultrastructural Pathology contains electron micrographs
acquired from my 40 years in the discipline at
four different institutions. Over 75 micrographs have
been contributed by electron microscopists working
in comparative or medical pathology—all micrographs
of exceptional quality.
To my many colleagues who have contributed to
this book, I am deeply grateful. I acknowledge in particular
the graduate students in veterinary pathology
who have contributed ideas and micrographs (see
dedication). The quality of electron micrographs is
due in no small way to the technical staff of the
National Animal Disease Center, particularly Judy
Stasko, Karen Schlueter, Doris Buck, and James Heminover.
Gene Hedberg has done outstanding work on
many of the line drawings, and preparation of micrographs
has been done by Wayne Romp and Tom
Glasson. I am also grateful to the staff of Wiley-
Blackwell, who have done a patient job of managing
and editing the manuscript.