W. Walther – Gene Therapy of Solid Cancers (2015)
1.930 ₽
Автор: W. Walther
Название книги: Gene Therapy of Solid Cancers
Формат: PDF
Жанр: Биологические науки
Страницы: 403
Качество: Изначально компьютерное, E-book
This volume provides insight into recent developments on experimental and clinical strategies for cancer gene therapy. Gene Therapy of Solid Cancers: Methods and Protocols guides readers throughprotocols on gene therapeutic strategies in combination with helpful technical notes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Concise and easy-to-use, Gene Therapy of Solid Cancers: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Aptamer Targeting the ERBB2 Receptor Tyrosine Kinase for Applications in Tumor Therapy
Gene Gun Her2/neu DNA Vaccination: Evaluation of Vaccine Efficacy in a Syngeneic Her2/neu Mouse Tumor Model
MIDGE Technology for the Production of a Fourfold Gene-Modified, Allogenic Cell-Based Vaccine for Cancer Therapy
Evaluation of Bystander Cell Killing Effects in Suicide Gene Therapy of Cancer: Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis
Oncoleaking: Use of the Pore-Forming Clostridium perfringens Enterotoxin (CPE) for Suicide Gene Therapy
iCaspase 9 Suicide Gene System
p53-Encoding pDNA Purification by Affinity Chromatography for Cancer Therapy
A qRT-PCR Method for Determining the Biodistribution Profile of a miR-34a Mimic
Design and Selection of Antisense Oligonucleotides Targeting Transforming Growth Factor Beta (TGF-β) Isoform mRNAs for the Treatment of Solid Tumors
RNA Interference for Antimetastatic Therapy
STAT3 Decoy ODN Therapy for Cancer
Oncolytic Viral Therapy Using Reovirus
Use of GLV-1h68 for Vaccinia Virotherapy and Monitoring
Back to the Future: Are Tumor-Targeting Bacteria the Next-Generation Cancer Therapy?
Ethics of Cancer Gene Transfer Clinical Research
Planning an Academic Clinical Trial
Production of Plasmid DNA as Pharmaceutical
Minicircle: Next Generation DNA Vectors for Vaccination
A Phase 2, Open-Label, Randomized Study of Pexa-Vec (JX-594) Administered by Intratumoral Injection in Patients with Unresectable Primary Hepatocellular Carcinoma
Antiangiogenic Metargidin Peptide (AMEP) Gene Therapy in Disseminated Melanoma
Описание
W. Walther – Gene Therapy of Solid Cancers (2015) — это специализированное руководство, которое подробно рассматривает современные подходы генной терапии солидных опухолей. Книга объясняет молекулярные механизмы, векторы доставки генов и стратегии таргетирования раковых клеток в тканях.
Авторы анализируют актуальные методы, включая использование вирусных и невирусных векторов, suicide-гены, иммуногенные подходы и комбинированную терапию. Особое внимание уделяется преодолению барьеров доставки в плотные опухоли и оценке эффективности на доклинических и клинических моделях.
- онкологам и исследователям, работающим в области молекулярной онкологии
- специалистам по генной и клеточной терапии
- студентам старших курсов и аспирантам биологических и медицинских специальностей
- врачам, интересующимся новейшими направлениями лечения рака
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