R. Gelpi – Biochemistry of Oxidative Stress. Physiopathology and Clinical Aspects (2016)

3.440 ₽

Автор: R. Gelpi
Название книги: Biochemistry of Oxidative Stress
Формат: PDF
Жанр: Медицина
Страницы: 448
Качество: Изначально компьютерное, E-book

The strongest point of this book titled “Biochemistry of Oxidative Stress: Physiopathology and Clinical Aspects”, is that the academic and scientific background of the authors/editors guarantee the authorship of a book comprising all aspects of oxidative stress, ranging from very molecular aspects, to clinical application, including the antioxidant therapy. Of particular importance is the fact that the aforementioned aspects are described in the book in a general section and in three different and important pathologies, such as cardiovascular diseases, neurodegenerative diseases, and cancer. The importance of these pathologies lays in the fact that, taken separately or together, they represent by far the leading cause of death in the world. Finally, all the chapters have been written by highly recognized authorities in the field of their investigations. At least to our knowledge, this is the first book with this characteristics in the field of oxidative stress.
General Aspects
The Concept of Oxidative Stress After 30 Years
The Evolution of the Earth and Its Atmosphere
Mitochondria Are the Main Cellular Source of O2 − , H2O2 and Oxidative Stress
Biochemistry and Physiology of Heart Mitochondrial Nitric Oxide Synthase
Biochemistry of Nitric Oxide and Peroxynitrite: Sources, Targets and Biological Implications
Nitro-arachidonic Acid: Downstream Signaling and Therapeutics
Mitochondrial Transfer by Intercellular Nanotubes
Human Adaptation to Life at High Altitude
Cardiovascular Diseases
Role of Oxidative Stress in Subcellular Defects in Ischemic Heart Disease
Reduced Oxidative Stress as a Mechanism for Increased Longevity, Exercise and Heart Failure
Protection with Adenylyl Cyclase Type 5 Inhibition
Regulation of Protein Nitrosylation by Thioredoxin
Thioredoxin Attenuates Post-ischemic Damage in Ventricular and Mitochondrial Function
Antioxidant Supplementation in Cardiovascular Disease and Hypertension
Oxidative Stress Influence in the Development of Pulmonary Arterial Hypertension
Redox Regulation of Vascular Remodeling
Mitochondrial Complex I Inactivation After Ischemia-Reperfusion in the Stunned Heart .
Reactive Oxygen Species Are Involved in Myocardial Remote Ischemic Preconditioning
Inhaled Particulate Matter Leads to Myocardial Dysfunction
Neuronal Function and Neurodegeneration
Neurovascular Coupling Mediated by Neuronal Derived-Nitric Oxide: Mechanisms in Health and Dysfunction with Impact on Aging and Alzheimer’s Disease
Oxidative Stress and Neurodegeneration
Mitochondrial DNA Damage in Autism
Systemic Oxidative Stress in Patients with Neurodegenerative Diseases
Metabolic Syndrome and Cancer
Oxidative Stress, Metabolic Syndrome and Alzheimer’s Disease
Oxidative Stress and Antioxidants in Experimental Metabolic Syndrome
Mitochondrial Dynamics Regulates Oxidative Metabolism in Leydig Tumor Cells
and Ernesto J. Podestá
Cancer and Mitochondria
Tumor Immunology and Immunotherapy in Cancer Patients

Описание

Книга R. Gelpi – Biochemistry of Oxidative Stress. Physiopathology and Clinical Aspects (2016) представляет собой современный обзор биохимических механизмов окислительного стресса и его роли в развитии заболеваний. Автор подробно разбирает, как нарушение баланса между образованием активных форм кислорода и антиоксидантной защитой влияет на клетки, ткани и целые органы.

Издание объединяет фундаментальные исследования молекулярных путей окислительного повреждения с клиническими аспектами: от сердечно-сосудистых и нейродегенеративных заболеваний до воспалительных процессов и онкологии. Особое внимание уделено биомаркерам, методам оценки окислительного стресса и потенциальным терапевтическим подходам.

  • студентам и аспирантам медицинских и биологических специальностей
  • врачам-исследователям в области патофизиологии и лабораторной диагностики
  • специалистам по биохимии и молекулярной медицине
  • учёным, изучающим механизмы старения и хронических заболеваний

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