P. Mehdipour – Epigenetics Territory and Cancer (2015)

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Автор: P. Mehdipour
Название книги: Epigenetics Territory and Cancer
Формат: PDF
Жанр: Биологические науки
Страницы: 538
Качество: Изначально компьютерное, E-book

Presents original research data in figures that illustrate new insights in cancer epigenetics
Collates fundamentals of epigenetics, the latest research and therapeutic design in treatment of cancer
Explores links between cancer research, medicine, and anthropology
This book explores epigenetic strategies, bridging fundamental cancer epigenetics, different paradigms in tumor genetics and translational understanding for both the clinic and improved lifestyles. The work provides target-based insights for treating different types of cancers and presents research on evolutionary epigenetics, introducing ‘Medical Epi- Anthropology’ and ‘Cancer Epi-Anthropology’. Translating multi-disciplinary research into therapeutic design is at the core of this book. Readers may explore how cancer management involves unmasking the involved networks and the interactive status of different genes to achieve the appropriate methylome based therapy. Early chapters explore fundamental aspects and brain tumours, whilst later chapters investigate breast cancer and various other cancers, and the final chapter presents an evolutionary insight in cancer epigenetics, considering that the epigene is beyond DNA methylation, RNA interference and histone modification in cancer development. This book will be of interest to researchers in different medical and scientific fields, including clinical management (diagnosis, prognosis, prediction, prevention, and guidelines), genetic education, nutrition and nutrigenomics, industrial chemistry, and drug innovation. Because of the unique bridging between science and medicine this book will also be useful as an educational and translational research package.
Table of contents
Fundamental Aspects of Epigenetic in Cancer
Biodynamic Phenotypic and Epigenetics Changes of Circulating Tumor Cells: Their Application in Cancer Prognosis and Treatment
LINE-1 Retrotransposons and Their Role in Cancer
Reciprocal Interconnection of miRNome-Epigenome in Cancer Pathogenesis and Its Therapeutic Potential
Reduced Risk of Cancer in Schizophrenia, a Bridge Toward Etio-Pathology and Therapy of Both Diseases
Exploring ATM and Methylation in Cancer: Emphasizing on Brain Tumors
Molecular and Biological Aspects of
Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors
Predictive Role of O6-Methylguanine DNA Methyltransferase Status for the Treatment of Brain Tumors
Epigenetics and Three Main Clinical Aspects of Breast Cancer Management
Epigenetic of Retinoic Acid Receptor β2 Gene in Breast Cancer
Retinoic Acid Receptor-β, From Gene to Clinic
Methylation in Colorectal Cancer
Malignant Rhabdoid Tumor: Epigenetic Mechanism of Tumorogenesis
Epigenetics of Thyroid Cancer
An Introduction to Impact of Bio-Resonance Technology in Genetics and Epigenetics
Essence of Cancer Epigenetic: A Harmonic Art for the Future

Описание

P. Mehdipour – Epigenetics Territory and Cancer (2015) — фундаментальная монография, посвященная роли эпигенетических механизмов в развитии, прогрессировании и лечении онкологических заболеваний. Книга объединяет актуальные данные о том, как метилирование ДНК, модификации гистонов, микроРНК и другие эпигенетические регуляторы влияют на поведение опухолевых клеток.

Автор подробно рассматривает территориальный и географический аспекты эпигенетических изменений, связь эпигенетики с окружающей средой, наследственностью и индивидуальными особенностями пациентов. Особое внимание уделяется возможностям эпигенетической терапии, биомаркерам и персонализированному подходу в онкологии.

  • специалистам в области онкологии и молекулярной биологии
  • врачам-онкологам, интересующимся таргетной и персонализированной терапией
  • исследователям и аспирантам, работающим в сфере эпигенетики и рака
  • биологам и генетикам, изучающим механизмы регуляции генома

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