Mihai D. Niculescu – Nutrition in Epigenetics

Автор: Mihai D. Niculescu
Название книги: Nutrition in Epigenetics
Формат: PDF
Жанр: Эпигенетика
Страницы: 359
Качество: Изначально компьютерное, E-book

The study of epigenetics, or how heritable changes in gene expression are regulated without modifying the coding DNA sequence, has become an increasingly important field of study in recent years. Rapid developments in our understanding of the way in which gene function is modulated by the environment has revolutionized the way we think about human development and health. Nutrition in Epigenetics reviews the latest research looking at the interaction between genes and nutrients and the role they play together in maintaining human health.
Nutrition in Epigenetics is divided into two primary parts. The first part provides key principles such as epigenetic mechanisms, developmental epigenetics, and the role of epigenetics in disease. The second part looks specifically at the application of epigenetics to the field of human nutrition. Chapters review the role of specific nutrients in modulating epigenetic status and the effect on health and disease.
Nutrition in Epigenetics is an indispensable resource for researchers, professionals and advanced students with an interest in human nutrition, epigenetics, and biomedical research.
Introduction
DNA Methylation
Chromatin Modifications
Roles of RNAi and Other MicroRNAs in the Regulation of Epigenetic Processes
Epigenetic Inheritance: Both Mitotic and Meiotic
Developmental Epigenetics: Roles in Embryonic Development
Epigenetics, Nutrition, and Cancer
Metabolic Syndrome, Obesity, and Diabetes
Autoimmunity
Cardiovascular Diseases
Maternal Nutrition and Developmental Outcomes
Folate, Vitamin B12, and Vitamin B6
Dietary Choline, Betaine, Methionine, and Epigenetic Mechanisms Influencing Brain Development
Epigenetic Regulation by Retinoids
We are WhatWe Eat: How Nutritional Compounds Such As Isoflavones Shape Our Epigenome
Isothiocyanates and Polyphenols
The Effect of Maternal Macronutrient Intake on Phenotype Induction and Epigenetic Gene Regulation
Epigenetic Manifestation of Environmental Exposures
Epigenetics, Nutrition, and Reproduction: Short- and Long-Term Consequences
Nutrition, Epigenetics, and Cancer: An Epidemiological Perspective